Improve sensitivity for antisense oligonucleotides quantification in plasma using MicroLC-MRM methodology

image006 - Improve sensitivity for antisense oligonucleotides quantification in plasma using MicroLC-MRM methodology

Latest methods on RNA analysis from small to large

This info kit from SCIEX provides information on the latest methods for RNA and oligonucleotide analysis using capillary electrophoresis (CE) and liquid chromatography mass spectrometry (LC-MS). It contains webinar links, the latest technical and application notes, posters and presentations by leaders in the field.

Learning points:

  • Discover how CE is used to profile oligonucleotides and RNA/DNA products used in the biopharmaceutical industry
  • Understand how CE is being used in the development of CRISPR
  • Learn how to detect oligonucleotides in plasma at 1 ng/mL
  • Find out how LC-MS can distinguish metabolites and impurities from full-length synthetic oligonucleotides

Download the info kit to see how oligonucleotides are analyzed today using CE and LC-MS technology.

image005 - Improve sensitivity for antisense oligonucleotides quantification in plasma using MicroLC-MRM methodology

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